Design and chemical syntheses of potent matriptase-2 inhibitors based on trypsin inhibitor SFTI-1 isolated from sunflower seeds

Agata Gitlin-Domagalska , Dawid Dębowski , Anna Łęgowska , Marit Stirnberg , Joanna Okońska , Michael Gütschow , Krzysztof Rolka

Abstract

n/a
Author Agata Gitlin-Domagalska (FCh / DMB / LBCh)
Agata Gitlin-Domagalska,,
- Laboratory of Bioorganic Chemistry
, Dawid Dębowski (FCh / DMB / LBCh)
Dawid Dębowski,,
- Laboratory of Bioorganic Chemistry
, Anna Łęgowska (FCh / DMB / LBCh)
Anna Łęgowska,,
- Laboratory of Bioorganic Chemistry
, Marit Stirnberg
Marit Stirnberg,,
-
, Joanna Okońska (FCh / DMB / LBCh)
Joanna Okońska,,
- Laboratory of Bioorganic Chemistry
, Michael Gütschow
Michael Gütschow,,
-
, Krzysztof Rolka (FCh / DMB / LBCh)
Krzysztof Rolka,,
- Laboratory of Bioorganic Chemistry
Journal seriesBiopolymers, ISSN 0006-3525, e-ISSN 1097-0282, (A 25 pkt)
Issue year2017
Vol108
No6
Pages1-11
Keywords in Englishenzyme, inhibitors, matriptase-1, matriptase-2
ASJC Classification1605 Organic Chemistry; 2502 Biomaterials; 1303 Biochemistry; 2700 General Medicine; 1304 Biophysics
DOIDOI:10.1002/bip.23031
URL http://onlinelibrary.wiley.com/doi/10.1002/bip.23031/epdf
Languageen angielski
Score (nominal)25
ScoreMinisterial score = 25.0, 24-07-2019, ArticleFromJournal
Publication indicators WoS Citations = 3; Scopus SNIP (Source Normalised Impact per Paper): 2016 = 0.722; WoS Impact Factor: 2017 = 1.99 (2) - 2017=2.165 (5)
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