Metody in-vivo badania właściwości antyoksydacyjnych związków kompleksowych
Jacek Malinowski , Joanna Drzeżdżon , Lech Chmurzyński , Dagmara Jacewicz
AbstractThis article describes the in-vivomethods of studying the antioxidant properties of complex compounds. The reduced glutathione (GSH) method, which uses the reactivity of the reduced form of GSH with free radicals, is among the described methods. Further the in-vivomethods are based on the use of antioxidant enzymes such as glutathione peroxidase, glutathione S-transferase, superoxide dismutase, catalase. These types of enzymes occur naturally in the human body and they are responsible for the inactivation of free radicals, e. g.superoxide dismutase catalyzes the reaction of disproportionation of superoxide anion radical to water and oxygen. The next in-vivomethods described in this article use γ-glutamyl transpeptidase and glutathione reductase, which are components of the antioxidant mechanism occurring in an organism. The last method described in this work relates to the lipid peroxidation, which is determined by the concentration of dimalonic aldehyde.
|Other language title versions||In-vivo methods for testing of the antioxidant properties of complex compounds|
|Journal series||Wiadomości Chemiczne, ISSN 0043-5104, e-ISSN 2300-0295, (B 7 pkt)|
|Publication size in sheets||0.75|
|Keywords in Polish||właściwości przeciwutleniające, rodniki, metody in-vivo|
|Keywords in English||antioxidant properties, radicals, in-vivo methods|
|Score|| = 7.0, 16-07-2019, ArticleFromJournal|
= 7.0, 16-07-2019, ArticleFromJournal
* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or Perish system.