New N-substituted hydrazones, derivatives of uridyl aldehyde
Katarzyna Kral , Tadeusz Bieg , Agnieszka Kudelko , Anna Barabaś , Aleksandra Dąbrowska , Ilona Wandzik
AbstractN-substituted isomeric hydrazones of uridyl aldehyde have been synthesized. The occurrence of the dominant E isomers with respect to the azomethine group was confirmed by means of NMR spectroscopy. Synthesized hydrazones feature an acetonide moiety as a protection of two hydroxyl groups on the ribose part. The attempt to remove the protecting group resulted in an azo-hydrazone tautomeric mixture. The described compounds may be valuable chiral ligands for metal chelation. Assessment of manganese(II) ion affinity to one selected hydrazone was performed.
|Journal series||Nucleosides Nucleotides & Nucleic Acids, ISSN 1525-7770 [1532-2335]|
|Publication size in sheets||0.5|
|Keywords in English||Uridine, N-acyl hydrazone, chelate formation|
|Score|| = 15.0, 20-12-2017, ArticleFromJournal|
= 15.0, 20-12-2017, ArticleFromJournal
|Publication indicators||: 2016 = 0.868 (2) - 2016=0.888 (5)|
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