Simultaneous determination of thermodynamic and kinetic parameters of aminopolycarbonate complexes of cobalt(II) and nickel(II) based on isothermal titration calorimetry data

Aleksandra Tesmar , Dariusz Wyrzykowski , Eva Muñoz , Bogusław Pilarski , Joanna Pranczk , Dagmara Jacewicz , Lech Chmurzyński


The influence of the different side chain residues on the thermodynamic and kinetic parameters for complexation reactions of the Co 2+ and Ni 2+ ions has been investigated by using the iso- thermal titration calorimetry (ITC) technique supported by potentiometric titration data. The study was concerned with the 2 common tripodal aminocarboxylate ligands, namely, nitrilotriacetic acid and N‐(2‐hydroxyethyl) iminodiacetic acid. Calorimetric measurements (ITC) were run in the 2‐(N‐morpholino)ethanesulfonic acid hydrate (2‐(N‐morpholino) ethanesulfonic acid), piperazine‐N,N′‐bis(2‐ethanesulfonic acid), and dimethylarsenic acid buffers (0.1 mol L −1 , pH 6) at 298.15 K. The quantification of the metal‐buffer interactions and their incorporation into the ITC data analysis enabled to obtain the pH‐independent and buffer‐independent thermodynamic parameters (K, ΔG, ΔH, and ΔS) for the reactions under study. Furthermore, the kinITC method was applied to obtain kinetic information on complex- ation reactions from the ITC data. Correlations, based on kinetic and thermodynamic data, between the kinetics of formation of Co 2+ and Ni 2+ complexes and their thermodynamic stabil- ities are discussed.
Author Aleksandra Tesmar (FCh / DGICh / LPCC)
Aleksandra Tesmar,,
- Laboratory of Physicochemistry of Coordination Complexes
, Dariusz Wyrzykowski (FCh / DGICh / LPCC)
Dariusz Wyrzykowski,,
- Laboratory of Physicochemistry of Coordination Complexes
, Eva Muñoz
Eva Muñoz,,
, Bogusław Pilarski
Bogusław Pilarski,,
, Joanna Pranczk (FCh / DGICh / LPCC)
Joanna Pranczk,,
- Laboratory of Physicochemistry of Coordination Complexes
, Dagmara Jacewicz (FCh / DGICh / LPCC)
Dagmara Jacewicz,,
- Laboratory of Physicochemistry of Coordination Complexes
, Lech Chmurzyński (FCh / DGICh / LPCC)
Lech Chmurzyński,,
- Laboratory of Physicochemistry of Coordination Complexes
Journal seriesJournal of Molecular Recognition, ISSN 0952-3499, (A 25 pkt)
Issue year2017
Publication size in sheets0.5
Keywords in Englishbuffer, Co(II) and Ni(II) complexes, competitive binding, isothermal titration calorimetry, kinITC method, thermodynamic parameters
Languageen angielski
Score (nominal)25
ScoreMinisterial score = 25.0, ArticleFromJournal
Ministerial score (2013-2016) = 25.0, ArticleFromJournal
Publication indicators WoS Impact Factor: 2017 = 1.868 (2) - 2017=1.901 (5)
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