Synthesis, QSAR studies, and metabolic stability of novel 2-alkylthio-4-chloro-N-(5-oxo-4,5-dihydro-1,2,4-triazin-3-yl)benzenesulfonamide derivatives as potential anticancer and apoptosis-inducing agents

Beata Żołnowska , Jarosław Sławiński , Aneta Pogorzelska , Krzysztof Szafrański , Anna Kawiak , Grzegorz Stasiłojć , Mariusz Belka , Joanna Zielińska , Tomasz Bączek

Abstract

n/a
Author Beata Żołnowska
Beata Żołnowska,,
-
, Jarosław Sławiński
Jarosław Sławiński,,
-
, Aneta Pogorzelska
Aneta Pogorzelska,,
-
, Krzysztof Szafrański
Krzysztof Szafrański,,
-
, Anna Kawiak KB
Anna Kawiak,,
- Department of Biotechnology
, Grzegorz Stasiłojć KBM
Grzegorz Stasiłojć,,
- Department of Medical Biotechnology
, Mariusz Belka
Mariusz Belka,,
-
, Joanna Zielińska
Joanna Zielińska,,
-
, Tomasz Bączek
Tomasz Bączek,,
-
Journal seriesChemical Biology & Drug Design, ISSN 1747-0277
Issue year2017
Vol90
No3
Pages380-396
Keywords in Englishanticancer, apoptosis, benzenesulfonamide, metabolic stability, mitochondrial membrane potential, QSAR, synthesis
DOIDOI:10.1111/cbdd.12955
URL http://onlinelibrary.wiley.com/doi/10.1111/cbdd.12955/epdf
Languageen angielski
Score (nominal)25
ScoreMinisterial score = 25.0, 26-01-2018, ArticleFromJournal
Ministerial score (2013-2016) = 25.0, 26-01-2018, ArticleFromJournal
Publication indicators WoS Impact Factor: 2016 = 2.396 (2) - 2016=2.473 (5)
Citation count*0
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* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or Perish system.
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