Phage therapy: beyond antibacterial action

Andrzej Górski , Ewa Jończyk-Matysiak , Ryszard Międzybrodzki , Beata Weber-Dąbrowska , Marzanna Łusiak-Szelachowska , Natalia Bagińska , Jan Borysowski , Małgorzata B. Łobocka , Alicja Węgrzyn , Grzegorz Węgrzyn

Abstract

Until recently, phages were considered as mere “bacteria eaters” with potential for use in combating antimicrobial resistance. The real value of phage therapy assessed according to the standards of evidence-based medicine awaits confirmation by clinical trials. However, the progress in research on phage biology has shed more light on the significance of phages. Accumulating data indicate that phages may also interact with eukaryotic cells. How such interactions could be translated into advances in medicine (especially novel means of therapy) is discussed herein.
Author Andrzej Górski - [Ludwik Hirszfeld Institute of Immunology and Experimental Therapy of the Polish Academy of Sciences]
Andrzej Górski,,
-
-
, Ewa Jończyk-Matysiak - [Ludwik Hirszfeld Institute of Immunology and Experimental Therapy of the Polish Academy of Sciences]
Ewa Jończyk-Matysiak,,
-
-
, Ryszard Międzybrodzki - [Ludwik Hirszfeld Institute of Immunology and Experimental Therapy of the Polish Academy of Sciences]
Ryszard Międzybrodzki,,
-
-
, Beata Weber-Dąbrowska - [Ludwik Hirszfeld Institute of Immunology and Experimental Therapy of the Polish Academy of Sciences]
Beata Weber-Dąbrowska,,
-
-
, Marzanna Łusiak-Szelachowska - [Ludwik Hirszfeld Institute of Immunology and Experimental Therapy of the Polish Academy of Sciences]
Marzanna Łusiak-Szelachowska,,
-
-
, Natalia Bagińska - [Ludwik Hirszfeld Institute of Immunology and Experimental Therapy of the Polish Academy of Sciences]
Natalia Bagińska,,
-
-
, Jan Borysowski - [Medical University of Warsaw]
Jan Borysowski,,
-
-
, Małgorzata B. Łobocka - [Institute of Biochemistry and Biophysics of the Polish Academy of Sciences]
Małgorzata B. Łobocka,,
-
- Institute of Biochemistry and Biophysics of the Polish Academy of Sciences
, Alicja Węgrzyn - [Institute of Biochemistry and Biophysics of the Polish Academy of Sciences]
Alicja Węgrzyn,,
-
- Institute of Biochemistry and Biophysics of the Polish Academy of Sciences
, Grzegorz Węgrzyn (FB / DMoB)
Grzegorz Węgrzyn,,
- Department of Molecular Biology
Journal seriesFrontiers in Medicine, ISSN , e-ISSN 2296-858X, (0 pkt)
Issue year2018
Vol5
Pages1-8
Publication size in sheets1.2
Keywords in Englishphage, phage therapy, immunomodulation, inflammation, prophage induction
DOIDOI:10.3389/fmed.2018.00146
URL https://doi.org/10.3389/fmed.2018.00146
Languageen angielski
LicenseJournal (articles only); published final; Uznanie Autorstwa (CC-BY); with publication
Score (nominal)5
ScoreMinisterial score = 0.0, ArticleFromJournal
Ministerial score (2013-2016) = 5.0, ArticleFromJournal - czasopismo zagraniczne spoza list
Publication indicators Scopus Citations = 2; WoS Citations = 3
Citation count*4 (2019-04-22)
Cite
Share Share

Get link to the record


* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or Perish system.
Back