The multi-Leu peptide inhibitor discriminates between PACE4 and furin and exhibits antiproliferative effects on prostate cancer cells

Christine Levesque , Martin Fugère , Anna Kwiatkowska , Frédéric Couture , Roxane Desjardins , Sophie Routhier , Philippe Moussette , Adam Prahl , Bernard Lammek , Jon R. Appel , Richard A. Houghten , François D'Anjou , Yves Dory , Witold Neugebauer , Robert Day

Abstract

n/a
Author Christine Levesque - [Université de Sherbrooke]
Christine Levesque,,
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, Martin Fugère - [Université de Sherbrooke]
Martin Fugère,,
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, Anna Kwiatkowska (FCh / DOCh)
Anna Kwiatkowska,,
- Department of Organic Chemistry
, Frédéric Couture - [Université de Sherbrooke]
Frédéric Couture,,
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, Roxane Desjardins - [Université de Sherbrooke]
Roxane Desjardins,,
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, Sophie Routhier - [Université de Sherbrooke]
Sophie Routhier,,
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, Philippe Moussette - [Université de Sherbrooke]
Philippe Moussette,,
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, Adam Prahl (FCh / DOCh / LChB)
Adam Prahl,,
- Laboratory of Chemistry of Biopolymers
, Bernard Lammek (FCh / DOCh / LChB)
Bernard Lammek,,
- Laboratory of Chemistry of Biopolymers
, Jon R. Appel - [Torrey Pines Institute for Molecular Studies]
Jon R. Appel,,
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et al.`
Journal seriesJournal of Medicinal Chemistry, ISSN 0022-2623, [1520-4804], (A 45 pkt)
Issue year2012
Vol55
No23
Pages10501-10511
ASJC Classification3002 Drug Discovery; 1313 Molecular Medicine
DOIDOI:10.1021/jm3011178
URL http://pubs.acs.org/doi/pdf/10.1021/jm3011178
Languageen angielski
Score (nominal)45
Publication indicators WoS Citations = 30; Scopus Citations = 32; Scopus SNIP (Source Normalised Impact per Paper): 2014 = 1.699; WoS Impact Factor: 2012 = 5.614 (2) - 2012=5.383 (5)
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