Synthesis, biological activity and solution structure of new analogues of the antimicrobial Gramicidin S

Elżbieta Kamysz , Beata Mickiewicz , Wojciech Kamysz , Sylwia Bielińska , Sylwia Rodziewicz-Motowidło , Jerzy Ciarkowski

Abstract

n/a
Author Elżbieta Kamysz (FCh / DMBt / LChBM)
Elżbieta Kamysz,,
- Laboratory of Chemistry of Biological Macromolecules
, Beata Mickiewicz (FCh / DTCh)
Beata Mickiewicz,,
- Department of Theoretical Chemistry
, Wojciech Kamysz - [Gdanski Uniwersytet Medyczny]
Wojciech Kamysz,,
-
- Gdanski Uniwersytet Medyczny
, Sylwia Bielińska - [Gdanski Uniwersytet Medyczny]
Sylwia Bielińska,,
-
- Gdanski Uniwersytet Medyczny
, Sylwia Rodziewicz-Motowidło (FCh / DBCh / LMCh)
Sylwia Rodziewicz-Motowidło,,
- Laboratory of Medical Chemistry
, Jerzy Ciarkowski (FCh / DTCh / LMM)
Jerzy Ciarkowski,,
- Laboratory of Molecular Modeling
Journal seriesJournal of Peptide Science, ISSN 1075-2617, (A 20 pkt)
Issue year2011
Vol17
No3
Pages211-217
Keywords in Englishantimicrobial peptide, gramicidin S, amphipathicity, cyclic peptide synthesis, NMR, molecular dynamics, hemolysis, structure-activity relationship
ASJC Classification1605 Organic Chemistry; 3002 Drug Discovery; 3004 Pharmacology; 1312 Molecular Biology; 1313 Molecular Medicine; 2700 General Medicine; 1303 Biochemistry; 1315 Structural Biology
DOIDOI:10.1002/psc.1314
URL http://onlinelibrary.wiley.com/doi/10.1002/psc.1314/pdf
Languageen angielski
Score (nominal)25
Publication indicators WoS Citations = 9; Scopus Citations = 9; Scopus SNIP (Source Normalised Impact per Paper): 2017 = 0.739; WoS Impact Factor: 2011 = 1.799 (2) - 2011=1.714 (5)
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