Neurochemistry of the anterior thalamic nuclei
AbstractThis paper reviews the distribution of several bioactive substances and their possible physiological roles in the anterior thalamic nuclei of various species, with a special emphasis on the rat. The anterior thalamus is a part of extended hippocampal system and its significance for learning and memory processes is well known. Although our knowledge about a specific role of this brain structure has increased in recent years considerably, this is the first attempt to summarize neurochemical diversity of the anterior thalamus. The following groups of bioactive substances are reviewed: (1) classical neurotransmitters (gamma-aminobutyric acid, glutamate and aspartate, acetylcholine, serotonin) and their receptors, (2) calcium-binding proteins (calretinin, calbindin, parvalbumin), and (3) others (cocaine- and amphetamine regulated transcript, enkephalins, substance P). In order to extend our knowledge concerning exact functions of selected neurotransmitters and neuromodulators in the studied brain structure, the future studies should concentrate on potential alterations in the neurochemical profile during various pathological states which affect the anterior thalamic nuclei.
|Journal series||Molecular Neurobiology, ISSN 0893-7648, (A 40 pkt)|
|Publication size in sheets||0.75|
|Keywords in English||anterior thalamic nuclei, calcium-binding proteins, neurotransmitters, rat|
|Score|| = 40.0, ArticleFromJournal|
= 40.0, ArticleFromJournal
|Publication indicators||: 2017 = 5.076 (2) - 2017=5.136 (5)|
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