Spectroscopic verification of ionic matrices for MALDI analysis

Paulina Kobylis , Hanna Lis , Piotr Stepnowski , Magda Caban

Abstract

Ionic liquid matrices have been recognized for MALDI application since 2001. However, specific information about the physical and chemical properties, ionicity or proper nomenclature of new matrices has never been presented. The aim of this investigation was to determine the chemical and physical characteristics of ionic matrices using spectroscopic techniques (UV–Vis, IR, 1H NMR). 66 mixtures of acids (standard MALDI matrices) and bases (organic amines) were prepared. The results obtained show that 1H NMR analysis, with supporting information from IR analysis, was helpful in the determination of the ionic character of the new matrices. Furthermore, thermogravimetric and cryometric analyses enabled the examination of the melting and decomposition points, in addition to the physical state of the obtained products, necessary for the classification of the new matrices. As a result, only a few acid and base mixtures could be categorized as ionic liquid matrices. What is important is that there were liquid matrices without an ionic character, and solid matrices with an ionic character. Thereby, a new categorization of matrices was introduced.
Author Paulina Kobylis (FCh / DEA / LChER)
Paulina Kobylis,,
- Laboratory of Chemical Environmental Risks
, Hanna Lis (FCh / DEA / PAiMŚ)
Hanna Lis,,
- Pracownia Analityki i Monitoringu Środowiska
, Piotr Stepnowski (FCh / DEA / LChER)
Piotr Stepnowski,,
- Laboratory of Chemical Environmental Risks
, Magda Caban (FCh / DEA / PAiMŚ)
Magda Caban,,
- Pracownia Analityki i Monitoringu Środowiska
Journal seriesJournal of Molecular Liquids, ISSN 0167-7322, (A 30 pkt)
Issue year2019
Vol284
Pages328-342
Publication size in sheets0.7
Keywords in EnglishIonic liquid matrices Ionic matrices, matrix-assisted laser desorption/ionization, spectroscopic study
ASJC Classification2505 Materials Chemistry; 1606 Physical and Theoretical Chemistry; 1607 Spectroscopy; 3104 Condensed Matter Physics; 3107 Atomic and Molecular Physics, and Optics; 2504 Electronic, Optical and Magnetic Materials
DOIDOI:10.1016/j.molliq.2019.03.137
URL https://doi.org/10.1016/j.molliq.2019.03.137
Languageen angielski
Score (nominal)30
ScoreMinisterial score = 30.0, 24-07-2019, ArticleFromJournal
Publication indicators Scopus SNIP (Source Normalised Impact per Paper): 2016 = 1.212; WoS Impact Factor: 2017 = 4.513 (2) - 2017=3.929 (5)
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