Bacteriophages as factories for Eu2O3 nanoparticle synthesis
Piotr Golec , Kamila Żelechowska , Joanna Karczewska-Golec , Jakub Karczewski , Adam Leśniewski , Marcin Łoś , Grzegorz Węgrzyn , Andrzej Marian Kłonkowski
AbstractThe use of phage display to identify peptides with an ability to bind and synthesize Eu2O3 nanoparticles is demonstrated in this report. This is the first report of modified phages specifically binding a lanthanide. The peptides exposed on virions revealed very strong binding to Eu2O3 nanoparticles and the ability to catalyze Eu2O3 nanoparticles’ formation from Eu(OH)3 and Eu(NO3)3 solutions. The luminescence emission spectrum of Eu3+ ions indicated that these ions existed mostly in sites deviated from the inversion symmetry in crystalline Eu2O3 aggregates and gelatinous Eu(OH)3 precipitate. The ability of phage-displayed peptides to catalyze formation of Eu2O3 nanoparticles provides a useful tool for a low-cost and effective synthesis of lanthanide nanoparticles, which serve as attractive biomedical sensors or fluorescent labels, among their other applications.
|Journal series||Bioconjugate Chemistry, ISSN 1043-1802|
|Publication size in sheets||0.5|
|Score|| = 35.0, 20-12-2017, ArticleFromJournal|
= 40.0, 20-12-2017, ArticleFromJournal
|Publication indicators||: 2016 = 4.818 (2) - 2016=4.574 (5)|
* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or Perish system.