Cognitive inconsistency in bipolar patients is determined by increased intra-individual variability in initial phase of task performance

Pawel Krukow , Ola Szaniawska , Michał Harciarek , Małgorzata Plechawska-Wójcik , Kamil Jonak

Abstract

BackgroundBipolar patients show high intra-individual variability during cognitive processing. However, it is not known whether there are a specific fluctuations of variability contributing to the overall high cognitive inconsistency. The objective was to compare dynamic profiles of patients and healthy controls to identify hypothetical differences and their associations with overall variability and processing speed.MethodsChanges of reaction times iSD during processing speed test performance over time was measured by dividing the iSD for whole task into four consecutive parts. Motor speed and cognitive effort were controlled.ResultsPatients with BD exhibited significantly lower results regarding processing speed and higher intra-individual variability comparing with HC. The profile of intra-individual variability changes over time of performance was significantly different in BD versus HC groups: F(3, 207)=8.60, p<0.0001, ηp2=0.11. iSD of BD patients in the initial phase of performance was three times higher than in the last. There was no significant differences between four intervals in HC group. Inter-group difference in the initial part of the profiles was significant also after controlling for several cognitive and clinical variables.LimitationsApplied computer version of Cognitive Speed Test was relatively new and, thus, replication studies are needed. Effect seen in the present study is driven mainly by the BD type I.ConclusionsPatients with BD exhibits problems with setting a stimulus-response association in starting phase of cognitive processing. This deficit may negatively interfere with the other cognitive functions, decreasing level of psychosocial functioning, therefore should be explored in future studies.
Author Pawel Krukow
Pawel Krukow,,
-
, Ola Szaniawska
Ola Szaniawska,,
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, Michał Harciarek ZPKiN
Michał Harciarek,,
- Division of Clinical Psychology and Neuropsychology
, Małgorzata Plechawska-Wójcik
Małgorzata Plechawska-Wójcik,,
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, Kamil Jonak
Kamil Jonak,,
-
Other language title versions
Journal seriesJournal of Affective Disorders, ISSN 0165-0327
Issue year2017
Vol210
Pages222-225
Publication size in sheets0.5
Keywords in Englishbipolar disorder, processing speed, intra-individual variability, task-setting
DOIDOI:10.1016/j.jad.2016.12.050
URL http://doi.org/10.1016/j.jad.2016.12.050
Languageen angielski
Score (nominal)35
ScoreMinisterial score = 35.0, 20-12-2017, ArticleFromJournal
Ministerial score (2013-2016) = 35.0, 20-12-2017, ArticleFromJournal
Publication indicators WoS Impact Factor: 2016 = 3.432 (2) - 2016=3.845 (5)
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