Acyloxymethyl Esterification of Nodularin-R and Microcystin-LA Produces Inactive Protoxins that Become Reactivated and Produce Apoptosis inside Intact Cells

Lars Herfindal , Franciszek Kasprzykowski , Frank Schwede , Leszek Łankiewicz , Kari E. Fladmark , Joanna Łukomska , Matti Wahlsten , Kaarin Sivonen , Zbigniew Grzonka , Bernd Jastorff , Stein Ove Doskeland

Abstract

n/a
Author Lars Herfindal
Lars Herfindal,,
-
, Franciszek Kasprzykowski (FCh / DBCh / LMCh)
Franciszek Kasprzykowski,,
- Laboratory of Medical Chemistry
, Frank Schwede
Frank Schwede,,
-
, Leszek Łankiewicz
Leszek Łankiewicz,,
-
, Kari E. Fladmark
Kari E. Fladmark,,
-
, Joanna Łukomska
Joanna Łukomska,,
-
, Matti Wahlsten
Matti Wahlsten,,
-
, Kaarin Sivonen
Kaarin Sivonen,,
-
, Zbigniew Grzonka (FCh)
Zbigniew Grzonka,,
- Faculty of Chemistry
, Bernd Jastorff
Bernd Jastorff,,
-
et al.`
Journal seriesJournal of Medicinal Chemistry, ISSN 0022-2623 [1520-4804], (A 45 pkt)
Issue year2009
Vol52
No18
Pages5758-5762
DOIDOI:10.1021/jm900502e
URL http://pubs.acs.org/doi/pdf/10.1021/jm900502e
Languageen angielski
Score (nominal)45
Publication indicators WoS Impact Factor: 2009 = 4.802 (2) - 2009=5.173 (5)
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