The triple-sorbents solid-phase extraction for pharmaceuticals and estrogens determination in wastewater samples

Magda Caban , Hanna Lis , Paulina Kobylis , Piotr Stepnowski


In the presented study, the applicability of four sorbent materials (active carbon, neutral alumina, Primary and Secondary Amines (PSA), and Florosil) applied on top of a polymeric Strata-X column was tested to improve the solid-phase extraction of 15 analytes (pharmaceuticals and estrogens) from water. Deionized water and water fortified by humic acids (representatives of dissolved organic matter) were the tested matrices. The effect of water acidification was tested as well. The values of recovery show that sorbents often have different sorption features towards pharmaceuticals with acidic and basic functional groups. PSA shows sorption towards humic acids, thereby can minimize the matrix effect obtained during final quantification by chromatographic techniques coupled with mass spectrometry. The slight sorption of basic pharmaceuticals to humic acids was found out. Finally, a mixture of PSA and alumina was used, and the validated SPE-GC/MS(SIM) method was applied for raw and treated wastewater. A triple-sorbent solid-phase extraction cause lower matrix effect compared to the previous study. This small innovation in the SPE procedure (without any significant cost enhancement and extension of the duration) can have an impact on the quantification of the pharmaceuticals and estrogens, and improve the reliability of the results.
Author Magda Caban (FCh / DEA / PAiMŚ)
Magda Caban,,
- Pracownia Analityki i Monitoringu Środowiska
, Hanna Lis (FCh / DEA / PAiMŚ)
Hanna Lis,,
- Pracownia Analityki i Monitoringu Środowiska
, Paulina Kobylis (FCh / DEA / LChER)
Paulina Kobylis,,
- Laboratory of Chemical Environmental Risks
, Piotr Stepnowski (FCh / DEA / LChER)
Piotr Stepnowski,,
- Laboratory of Chemical Environmental Risks
Journal seriesMicrochemical Journal, ISSN 0026-265X, (N/A 70 pkt)
Issue year2019
Article number103965
Keywords in EnglishPharmaceutical residues, solid-phase extraction, matrix effect, wastewater, primary and secondary amines, alumina
ASJC Classification1607 Spectroscopy; 1602 Analytical Chemistry
Languageen angielski
Score (nominal)70
Score sourcejournalList
ScoreMinisterial score = 70.0, 10-01-2020, ArticleFromJournal
Publication indicators WoS Citations = 0; Scopus Citations = 0; Scopus SNIP (Source Normalised Impact per Paper): 2016 = 1.305; WoS Impact Factor: 2018 = 3.206 (2) - 2018=2.993 (5)
Citation count*1 (2020-01-08)
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