Bioaccumulation and analytics of pharmaceutical residues in the environment : a review

Alan Puckowski , Katarzyna Mioduszewska , Paulina Łukaszewicz , Marta Borecka , Magda Caban , Joanna Maszkowska , Piotr Stepnowski

Abstract

The presence of pharmaceutical residues in various environmental compartments is an issue of increasing concern. The widespread occurrence of these compounds in water and soil samples has been demonstrated in a number of analytical studies. However, the data about their concentrations in biota samples is scarce. Moreover, the trophic transfer of pharmaceuticals remains largely unexplored, despite increasing evidence of the potential bioaccumulation of those compounds. Therefore, the main aim of this review is to present an overview of the current state of data about the bioaccumulation and analytical methodologies used for the determination of pharmaceutical residues in biota samples. This work focuses on the most commonly found pharmaceuticals in the environment: antibiotics, analgesic and anti-inflammatory drugs, steroid hormones, antihypertensives and antidepressants. We do hope that the collected data will allow a better understanding of pharmaceutical pollution and the exposure of non-target organisms. However, although impressive progress has undoubtedly been made, in order to fully understand the behavior of these chemicals in the environment, there are still numerous gaps to be filled in our overall knowledge in this field.
Author Alan Puckowski PChZŚ
Alan Puckowski,,
- Laboratory of Chemical Environmental Risks
, Katarzyna Mioduszewska PChZŚ
Katarzyna Mioduszewska,,
- Laboratory of Chemical Environmental Risks
, Paulina Łukaszewicz PChZŚ
Paulina Łukaszewicz,,
- Laboratory of Chemical Environmental Risks
, Marta Borecka PChZŚ
Marta Borecka,,
- Laboratory of Chemical Environmental Risks
, Magda Caban PAiMŚ
Magda Caban,,
- Pracownia Analityki i Monitoringu Środowiska
, Joanna Maszkowska PChZŚ
Joanna Maszkowska,,
- Laboratory of Chemical Environmental Risks
, Piotr Stepnowski PChZŚ
Piotr Stepnowski,,
- Laboratory of Chemical Environmental Risks
Journal seriesJournal of Pharmaceutical and Biomedical Analysis, ISSN 0731-7085
Issue year2016
Vol127
Pages232-255
Publication size in sheets1.15
Keywords in Englishpharmaceutical residues, biota samples, bioaccumulation, bioanalysis, ecotoxicity
DOIDOI:10.1016/j.jpba.2016.02.049
URL http://dx.doi.org/10.1016/j.jpba.2016.02.049
Languageen angielski
Score (nominal)35
ScoreMinisterial score = 35.0, 20-12-2017, ArticleFromJournal
Ministerial score (2013-2016) = 35.0, 20-12-2017, ArticleFromJournal
Publication indicators WoS Impact Factor: 2016 = 3.255 (2) - 2016=2.953 (5)
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