Bioaccumulation and analytics of pharmaceutical residues in the environment: a review

Alan Puckowski , Katarzyna Mioduszewska , Paulina Łukaszewicz , Marta Borecka , Magda Caban , Joanna Maszkowska , Piotr Stepnowski


The presence of pharmaceutical residues in various environmental compartments is an issue of increasing concern. The widespread occurrence of these compounds in water and soil samples has been demonstrated in a number of analytical studies. However, the data about their concentrations in biota samples is scarce. Moreover, the trophic transfer of pharmaceuticals remains largely unexplored, despite increasing evidence of the potential bioaccumulation of those compounds. Therefore, the main aim of this review is to present an overview of the current state of data about the bioaccumulation and analytical methodologies used for the determination of pharmaceutical residues in biota samples. This work focuses on the most commonly found pharmaceuticals in the environment: antibiotics, analgesic and anti-inflammatory drugs, steroid hormones, antihypertensives and antidepressants. We do hope that the collected data will allow a better understanding of pharmaceutical pollution and the exposure of non-target organisms. However, although impressive progress has undoubtedly been made, in order to fully understand the behavior of these chemicals in the environment, there are still numerous gaps to be filled in our overall knowledge in this field.
Author Alan Puckowski (FCh / DEA / LChER)
Alan Puckowski,,
- Laboratory of Chemical Environmental Risks
, Katarzyna Mioduszewska (FCh / DEA / LChER)
Katarzyna Mioduszewska,,
- Laboratory of Chemical Environmental Risks
, Paulina Łukaszewicz (FCh / DEA / LChER)
Paulina Łukaszewicz,,
- Laboratory of Chemical Environmental Risks
, Marta Borecka (FCh / DEA / LChER)
Marta Borecka,,
- Laboratory of Chemical Environmental Risks
, Magda Caban (FCh / DEA / PAiMŚ)
Magda Caban,,
- Pracownia Analityki i Monitoringu Środowiska
, Joanna Maszkowska (FCh / DEA / LChER)
Joanna Maszkowska,,
- Laboratory of Chemical Environmental Risks
, Piotr Stepnowski (FCh / DEA / LChER)
Piotr Stepnowski,,
- Laboratory of Chemical Environmental Risks
Journal seriesJournal of Pharmaceutical and Biomedical Analysis, ISSN 0731-7085, (A 35 pkt)
Issue year2016
Publication size in sheets1.15
Keywords in Englishpharmaceutical residues, biota samples, bioaccumulation, bioanalysis, ecotoxicity
ASJC Classification1308 Clinical Biochemistry; 1607 Spectroscopy; 3002 Drug Discovery; 3003 Pharmaceutical Science; 1602 Analytical Chemistry
Languageen angielski
Score (nominal)35
Score sourcejournalList
ScoreMinisterial score = 35.0, 14-02-2020, ArticleFromJournal
Ministerial score (2013-2016) = 35.0, 14-02-2020, ArticleFromJournal
Publication indicators Scopus Citations = 76; WoS Citations = 60; Scopus SNIP (Source Normalised Impact per Paper): 2016 = 1.357; WoS Impact Factor: 2016 = 3.255 (2) - 2016=2.953 (5)
Citation count*102 (2020-02-23)
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* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or Perish system.
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