Recent trends in determination of neurotoxins in aquatic environmental samples

Małgorzata Rutkowska , Justyna Płotka-Wasylka , Tomasz Majchrzak , Wojciech Wojnowski , Hanna Mazur-Marzec , Jacek Namieśnik

Abstract

Anatoxins, saxitoxins, ciguatoxins, beta-N-methylamino-l-alanine and its isomers are groups of neurotoxins which have a highly specific effect on the nervous system of animals, including humans, by interfering with the transmission of nerve impulses. In order to assess the human exposure to these neurotoxins, selective, interlaboratory-validated analytical methods are being developed to facilitate obtaining reliable results on the levels of neurotoxins both in the water and in biological samples. The aim of this work is to provide an overview of the state of the art of analytical techniques used for isolation and determination of neurotoxins from samples of aquatic ecosystems. This work also constitutes an attempt to outline the current state of knowledge in regard to the occurrence of neurotoxic compounds in aquatic ecosystems on the basis of studies in which adequate analytical methods were used.
Author Małgorzata Rutkowska
Małgorzata Rutkowska,,
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, Justyna Płotka-Wasylka
Justyna Płotka-Wasylka,,
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, Tomasz Majchrzak
Tomasz Majchrzak,,
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, Wojciech Wojnowski
Wojciech Wojnowski,,
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, Hanna Mazur-Marzec (FOG / IO / DMarB)
Hanna Mazur-Marzec,,
- Division of Marine Biotechnology
, Jacek Namieśnik
Jacek Namieśnik,,
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Journal seriesTrac-Trends in Analytical Chemistry, ISSN 0165-9936, (A 50 pkt)
Issue year2019
Vol112
Pages112-122
Publication size in sheets0.5
Keywords in EnglishNeurotoxins, BMAA, anatoxins, saxitoxins, ciguatoxins, harmful algal bloom
DOIDOI:10.1016/j.trac.2019.01.001
URL https://doi.org/10.1016/j.trac.2019.01.001
Languageen angielski
Score (nominal)50
ScoreMinisterial score = 50.0, 05-03-2019, ArticleFromJournal
Ministerial score (2013-2016) [mainScore, reportSelectable] = 50.0, 05-03-2019, ArticleFromJournal
Publication indicators WoS Impact Factor: 2017 = 7.034 (2) - 2017=7.621 (5)
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