Comparison of the paracetamol electrochemical determination using boron-doped diamond electrode and boron-doped carbon nanowalls
Paweł Niedziałkowski , Zofia Cebula , Natalia Malinowska , Wioleta Białobrzeska , Michał Sobaszek , M. Ficek , Robert Bogdanowicz , J. Sein Anand , Tadeusz Ossowski
AbstractTwo different type of electrodes, boron-doped diamond electrode (BDD) and boron-doped carbon nanowalls (B:CNW) electrode, were used for the electrochemical determination of paracetamol using the cyclic voltammetry and the differential pulse voltammetry in phosphate buffered saline, pH =7.0. The main advantage of these electrodes is their utilization without any additional modification of the electrode surface. The peak current was linearly related to the concentration of paracetamol in the range from 0.065 μM to 32 μM for BDD electrode and from 0.032 μM to 32 μM for B:CNW electrode. The limit of detection was 0.430 μM and 0.281 μM for BDD and B:CNW electrode, respectively. Additionally, we studied the effect of pH on the redox reaction of paracetamol at the both electrodes in Britton-Robinson buffer solution in the range of pH 3.0–12.0, indicating the pH 7.0 value as the most suitable for the current experiments. The studies also included the various scan rates in range of 50–500 mV/s. Finally, our team selected the B:CNW electrode for the determination of paracetamol in the artificial urine sample using differential pulse voltammetry method, obtaining the calculated limit of detection on the level of 0.08006 μM.
|Journal series||Biosensors & Bioelectronics, ISSN 0956-5663, (A 40 pkt)|
|Publication size in sheets||0.5|
|Keywords in English||boron-doped diamond electrode, boron-doped carbon nanowalls electrode, cyclic voltammetry, differential pulse voltammetry, paracetamol|
|Score|| = 40.0, ArticleFromJournal|
= 40.0, ArticleFromJournal
|Publication indicators||: 2017 = 8.173 (2) - 2017=7.291 (5)|
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