Comparison of the paracetamol electrochemical determination using boron-doped diamond electrode and boron-doped carbon nanowalls

Paweł Niedziałkowski , Zofia Cebula , Natalia Malinowska , Wioleta Białobrzeska , Michał Sobaszek , M. Ficek , Robert Bogdanowicz , J. Sein Anand , Tadeusz Ossowski

Abstract

Two different type of electrodes, boron-doped diamond electrode (BDD) and boron-doped carbon nanowalls (B:CNW) electrode, were used for the electrochemical determination of paracetamol using the cyclic voltammetry and the differential pulse voltammetry in phosphate buffered saline, pH =7.0. The main advantage of these electrodes is their utilization without any additional modification of the electrode surface. The peak current was linearly related to the concentration of paracetamol in the range from 0.065 μM to 32 μM for BDD electrode and from 0.032 μM to 32 μM for B:CNW electrode. The limit of detection was 0.430 μM and 0.281 μM for BDD and B:CNW electrode, respectively. Additionally, we studied the effect of pH on the redox reaction of paracetamol at the both electrodes in Britton-Robinson buffer solution in the range of pH 3.0–12.0, indicating the pH 7.0 value as the most suitable for the current experiments. The studies also included the various scan rates in range of 50–500 mV/s. Finally, our team selected the B:CNW electrode for the determination of paracetamol in the artificial urine sample using differential pulse voltammetry method, obtaining the calculated limit of detection on the level of 0.08006 μM.
Author Paweł Niedziałkowski (FCh / DACh / LSCh)
Paweł Niedziałkowski,,
- Laboratory of Supramolecular Chemistry
, Zofia Cebula (FCh / DACh / LSCh)
Zofia Cebula,,
- Laboratory of Supramolecular Chemistry
, Natalia Malinowska (FCh / DACh / LSCh)
Natalia Malinowska,,
- Laboratory of Supramolecular Chemistry
, Wioleta Białobrzeska (FCh / DACh / LSCh)
Wioleta Białobrzeska,,
- Laboratory of Supramolecular Chemistry
, Michał Sobaszek
Michał Sobaszek,,
-
, M. Ficek
M. Ficek,,
-
, Robert Bogdanowicz
Robert Bogdanowicz,,
-
, J. Sein Anand
J. Sein Anand,,
-
, Tadeusz Ossowski (FCh / DACh / LSCh)
Tadeusz Ossowski,,
- Laboratory of Supramolecular Chemistry
Journal seriesBiosensors & Bioelectronics, ISSN 0956-5663, (A 40 pkt)
Issue year2019
Vol126
Pages308-314
Publication size in sheets0.5
Keywords in Englishboron-doped diamond electrode, boron-doped carbon nanowalls electrode, cyclic voltammetry, differential pulse voltammetry, paracetamol
DOIDOI:10.1016/j.bios.2018.10.063
URL https://doi.org/10.1016/j.bios.2018.10.063
Languageen angielski
Score (nominal)40
ScoreMinisterial score = 40.0, 21-11-2018, ArticleFromJournal
Ministerial score (2013-2016) = 40.0, 21-11-2018, ArticleFromJournal
Publication indicators WoS Impact Factor: 2016 = 7.78 (2) - 2016=6.862 (5)
Citation count*
Cite
Share Share

Get link to the record


* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or Perish system.
Back