Comparison of the paracetamol electrochemical determination using boron-doped diamond electrode and boron-doped carbon nanowalls

Paweł Niedziałkowski , Zofia Cebula , Natalia Malinowska , Wioleta Białobrzeska , Michał Sobaszek , M. Ficek , Robert Bogdanowicz , J. Sein Anand , Tadeusz Ossowski


Two different type of electrodes, boron-doped diamond electrode (BDD) and boron-doped carbon nanowalls (B:CNW) electrode, were used for the electrochemical determination of paracetamol using the cyclic voltammetry and the differential pulse voltammetry in phosphate buffered saline, pH =7.0. The main advantage of these electrodes is their utilization without any additional modification of the electrode surface. The peak current was linearly related to the concentration of paracetamol in the range from 0.065 μM to 32 μM for BDD electrode and from 0.032 μM to 32 μM for B:CNW electrode. The limit of detection was 0.430 μM and 0.281 μM for BDD and B:CNW electrode, respectively. Additionally, we studied the effect of pH on the redox reaction of paracetamol at the both electrodes in Britton-Robinson buffer solution in the range of pH 3.0–12.0, indicating the pH 7.0 value as the most suitable for the current experiments. The studies also included the various scan rates in range of 50–500 mV/s. Finally, our team selected the B:CNW electrode for the determination of paracetamol in the artificial urine sample using differential pulse voltammetry method, obtaining the calculated limit of detection on the level of 0.08006 μM.
Author Paweł Niedziałkowski (FCh / DACh / LSCh)
Paweł Niedziałkowski,,
- Laboratory of Supramolecular Chemistry
, Zofia Cebula (FCh / DACh / LSCh)
Zofia Cebula,,
- Laboratory of Supramolecular Chemistry
, Natalia Malinowska (FCh / DACh / LSCh)
Natalia Malinowska,,
- Laboratory of Supramolecular Chemistry
, Wioleta Białobrzeska (FCh / DACh / LSCh)
Wioleta Białobrzeska,,
- Laboratory of Supramolecular Chemistry
, Michał Sobaszek
Michał Sobaszek,,
, M. Ficek
M. Ficek,,
, Robert Bogdanowicz
Robert Bogdanowicz,,
, J. Sein Anand
J. Sein Anand,,
, Tadeusz Ossowski (FCh / DACh / LSCh)
Tadeusz Ossowski,,
- Laboratory of Supramolecular Chemistry
Journal seriesBiosensors & Bioelectronics, ISSN 0956-5663, (N/A 200 pkt)
Issue year2019
Publication size in sheets0.5
Keywords in Englishboron-doped diamond electrode, boron-doped carbon nanowalls electrode, cyclic voltammetry, differential pulse voltammetry, paracetamol
ASJC Classification1603 Electrochemistry; 2204 Biomedical Engineering; 2700 General Medicine; 1304 Biophysics; 1305 Biotechnology
Languageen angielski
Score (nominal)200
Score sourcejournalList
ScoreMinisterial score = 200.0, 28-01-2020, ArticleFromJournal
Publication indicators WoS Citations = 5; Scopus SNIP (Source Normalised Impact per Paper): 2018 = 1.781; WoS Impact Factor: 2018 = 9.518 (2) - 2018=8.037 (5)
Citation count*12 (2020-05-06)
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