The role of proteases in the virulence of plant pathogenic bacteria

Donata Figaj , Patrycja Ambroziak , Tomasz Przepióra , Joanna Skórko-Glonek


A pathogenic lifestyle is inextricably linked with the constant necessity of facing various challenges exerted by the external environment (both within and outside the host). To successfully colonize the host and establish infection, pathogens have evolved sophisticated systems to combat the host defense mechanisms and also to be able to withstand adverse environmental conditions. Proteases, as crucial components of these systems, are involved in a variety of processes associated with infection. In phytopathogenic bacteria, they play important regulatory roles and modulate the expression and functioning of various virulence factors. Secretory proteases directly help avoid recognition by the plant immune systems, and contribute to the deactivation of the defense response pathways. Finally, proteases are important components of protein quality control systems, and thus enable maintaining homeostasis in stressed bacterial cells. In this review, we discuss the known protease functions and protease-regulated signaling processes associated with virulence of plant pathogenic bacteria.
Author Donata Figaj (FB/DB)
Donata Figaj,,
- Department of Biochemistry
, Patrycja Ambroziak (FB)
Patrycja Ambroziak,,
- Faculty of Biology
, Tomasz Przepióra (FB/DB)
Tomasz Przepióra,,
- Department of Biochemistry
, Joanna Skórko-Glonek (FB/DB)
Joanna Skórko-Glonek,,
- Department of Biochemistry
Journal seriesInternational Journal of Molecular Sciences, ISSN 1422-0067, (N/A 140 pkt)
Issue year2019
Publication size in sheets1.45
Keywords in Englishplant pathogenic bacteria, bacterial virulence, regulatory proteolysis, extracellular proteases, effector proteases, T3SS
ASJC Classification2700 General Medicine; 1312 Molecular Biology; 1503 Catalysis; 1604 Inorganic Chemistry; 1605 Organic Chemistry; 1606 Physical and Theoretical Chemistry; 1607 Spectroscopy; 1706 Computer Science Applications
Languageen angielski
LicenseJournal (articles only); published final; Uznanie Autorstwa (CC-BY); with publication
Score (nominal)140
Score sourcejournalList
ScoreMinisterial score = 140.0, 14-08-2020, ArticleFromJournal
Publication indicators WoS Citations = 2.000; Scopus Citations = 5.000; Scopus SNIP (Source Normalised Impact per Paper): 2019 = 1.300; WoS Impact Factor: 2018 = 4.183 (2) - 2018=4.331 (5)
Citation count*8 (2020-07-17)
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* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or Perish system.
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