The role of proteases in the virulence of plant pathogenic bacteria

Donata Figaj , Patrycja Ambroziak , Tomasz Przepióra , Joanna Skórko-Glonek

Abstract

A pathogenic lifestyle is inextricably linked with the constant necessity of facing various challenges exerted by the external environment (both within and outside the host). To successfully colonize the host and establish infection, pathogens have evolved sophisticated systems to combat the host defense mechanisms and also to be able to withstand adverse environmental conditions. Proteases, as crucial components of these systems, are involved in a variety of processes associated with infection. In phytopathogenic bacteria, they play important regulatory roles and modulate the expression and functioning of various virulence factors. Secretory proteases directly help avoid recognition by the plant immune systems, and contribute to the deactivation of the defense response pathways. Finally, proteases are important components of protein quality control systems, and thus enable maintaining homeostasis in stressed bacterial cells. In this review, we discuss the known protease functions and protease-regulated signaling processes associated with virulence of plant pathogenic bacteria.
Author Donata Figaj (FB / DB)
Donata Figaj,,
- Department of Biochemistry
, Patrycja Ambroziak (FB)
Patrycja Ambroziak,,
- Faculty of Biology
, Tomasz Przepióra (FB / DB)
Tomasz Przepióra,,
- Department of Biochemistry
, Joanna Skórko-Glonek (FB / DB)
Joanna Skórko-Glonek,,
- Department of Biochemistry
Journal seriesInternational Journal of Molecular Sciences, ISSN 1422-0067, (A 30 pkt)
Issue year2019
Vol20
No3
Pages1-30
Publication size in sheets1.45
Keywords in Englishplant pathogenic bacteria, bacterial virulence, regulatory proteolysis, extracellular proteases, effector proteases, T3SS
DOIDOI:10.3390/ijms20030672
URL https://www.mdpi.com/1422-0067/20/3/672/pdf
Languageen angielski
LicenseJournal (articles only); published final; Uznanie Autorstwa (CC-BY); with publication
Score (nominal)30
ScoreMinisterial score = 30.0, ArticleFromJournal
Ministerial score (2013-2016) = 30.0, ArticleFromJournal
Publication indicators WoS Impact Factor: 2017 = 3.687 (2) - 2017=3.878 (5)
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