Preventing fibril formation of a protein by selective mutation

Gia G. Maisuradze , Jordi Medina , Khatuna Kachlishvili , Paweł Krupa , Magdalena Mozolewska , Pau Martin-Malpartida , Luka Maisuradze , Maria J. Macias , Harold A. Scheraga

Abstract

n/a
Author Gia G. Maisuradze
Gia G. Maisuradze,,
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, Jordi Medina
Jordi Medina,,
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, Khatuna Kachlishvili
Khatuna Kachlishvili,,
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, Paweł Krupa (FCh / DTCh / LSP)
Paweł Krupa,,
- Laboratory of Simulation of Polymers
, Magdalena Mozolewska (FCh / DTCh / LMM)
Magdalena Mozolewska,,
- Laboratory of Molecular Modeling
, Pau Martin-Malpartida
Pau Martin-Malpartida,,
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, Luka Maisuradze
Luka Maisuradze,,
-
, Maria J. Macias
Maria J. Macias,,
-
, Harold A. Scheraga
Harold A. Scheraga,,
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Journal seriesProceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, (A 45 pkt)
Issue year2015
Vol112
No44
Pages13549-13554
Keywords in Englishfibril formation, selective mutation, FBP28 WW domain, millisecond-timescale MD simulations, high-resolution NMR spectroscopy
DOIDOI:10.1073/pnas.1518298112
URL www.pnas.org/cgi/doi/10.1073/pnas.1518298112
Languageen angielski
Score (nominal)45
ScoreMinisterial score = 45.0, 20-12-2017, ArticleFromJournal
Ministerial score (2013-2016) = 45.0, 20-12-2017, ArticleFromJournal
Publication indicators WoS Impact Factor: 2015 = 9.423 (2) - 2015=10.285 (5)
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