Zanieczyszczenie środowiska niesteroidowymi lekami przeciwzapalnymi na przykładzie diklofenaku - przyczyny, skutki, bioindykacja
Darya Harshkova , Anna Aksmann
AbstractNon-steroidal anti-inflammatory drugs (NSAIDs) present in water environment can be dangerous to all levels of trophic food chains, including human health. Due to the continuous inflow of NSAIDs to ecosystems, existing data on contamination of environment with these compounds and their bioaccumulation potential, there is a need to monitor the environment for the presence of NSAIDs and their toxicity. An indispensable element of environmental research is bioindication, which allows to determine basic properties of an environment on the basis of responses of model bioindicators. One of the most toxic NSAIDs in the environment is diclofenac. Discrepancies in the sensitivity of bioindicators to diclofenac enforce a search for the causes of its toxicity at the subcellular level. The promising model indicator organism is Chlamydomonas reinhardtii, which can be used for toxicological analysis at the population, cellular, biochemical and molecular level. Studies of this organism can provide valuable information on the diclofenac toxicity towards algae and plants.
|Other language title versions||environmental pollution by non-steroidal anti-infammatory drugs - diclofenac as an example|
|Journal series||Kosmos, ISSN 0023-4249, (B 12 pkt)|
|Publication size in sheets||0.5|
|Keywords in Polish||bioindykacja, Chlamydomonas reinhardtii, diklofenak, niesteroidowe leki przeciwzapalne, NLPZ|
|Keywords in English||bioindication, Chlamydomonas reinhardtii, diclofenac, non-steroidal anti-inflammatory drugs, NSAIDs|
|Score||= 12.0, 24-07-2019, ArticleFromJournal|
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