Zanieczyszczenie środowiska niesteroidowymi lekami przeciwzapalnymi na przykładzie diklofenaku - przyczyny, skutki, bioindykacja

Darya Harshkova , Anna Aksmann

Abstract

Non-steroidal anti-inflammatory drugs (NSAIDs) present in water environment can be dangerous to all levels of trophic food chains, including human health. Due to the continuous inflow of NSAIDs to ecosystems, existing data on contamination of environment with these compounds and their bioaccumulation potential, there is a need to monitor the environment for the presence of NSAIDs and their toxicity. An indispensable element of environmental research is bioindication, which allows to determine basic properties of an environment on the basis of responses of model bioindicators. One of the most toxic NSAIDs in the environment is diclofenac. Discrepancies in the sensitivity of bioindicators to diclofenac enforce a search for the causes of its toxicity at the subcellular level. The promising model indicator organism is Chlamydomonas reinhardtii, which can be used for toxicological analysis at the population, cellular, biochemical and molecular level. Studies of this organism can provide valuable information on the diclofenac toxicity towards algae and plants.
Author Darya Harshkova (FB / DPPB)
Darya Harshkova,,
- Department of Plant Physiology and Biotechnology
, Anna Aksmann (FB / DPPB)
Anna Aksmann,,
- Department of Plant Physiology and Biotechnology
Other language title versionsenvironmental pollution by non-steroidal anti-infammatory drugs - diclofenac as an example
Journal seriesKosmos, ISSN 0023-4249, (B 12 pkt)
Issue year2019
Vol68
No1
Pages185-194
Publication size in sheets0.5
Keywords in Polishbioindykacja, Chlamydomonas reinhardtii, diklofenak, niesteroidowe leki przeciwzapalne, NLPZ
Keywords in Englishbioindication, Chlamydomonas reinhardtii, diclofenac, non-steroidal anti-inflammatory drugs, NSAIDs
URL https://kosmos.ptpk.org/index.php/Kosmos/article/view/2487/2503
Languagepl polski
Score (nominal)12
ScoreMinisterial score = 12.0, 24-07-2019, ArticleFromJournal
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