A disulfide tether stabilizes the block of sodium channels by the conotoxin μO§-GVIIJ

Joanna Gajewiak , Layla Azam , Julita Imperial , Aleksandra Walewska , Brad R. Green , Pradip K. Bandyopadhyay , Shrinivasan Raghuraman , Beatrix Ueberheide , Marshall Bern , H. Mimi Zhou , Natali A. Minassian , Rebecca H. Hagan , Mack Flinspach , Yi Liu , Grzegorz Bulaj , Alan D. Wickenden , Baldomero M. Olivera , Doju Yoshikam , Min-Min Zhang

Abstract

n/a
Author Joanna Gajewiak
Joanna Gajewiak,,
-
, Layla Azam
Layla Azam,,
-
, Julita Imperial
Julita Imperial,,
-
, Aleksandra Walewska PChP
Aleksandra Walewska,,
- Laboratory of Chemistry of Biopolymers
, Brad R. Green
Brad R. Green,,
-
, Pradip K. Bandyopadhyay
Pradip K. Bandyopadhyay,,
-
, Shrinivasan Raghuraman
Shrinivasan Raghuraman,,
-
, Beatrix Ueberheide
Beatrix Ueberheide,,
-
, Marshall Bern
Marshall Bern,,
-
, H. Mimi Zhou
H. Mimi Zhou,,
-
et al.`
Journal seriesProceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424
Issue year2014
Vol111
No7
Pages2758-2763
Keywords in Englishdisulfide exchange, Navβ-subunit, tethered toxin, voltage-gated sodium channel, S-cysteinylation
DOIDOI:10.1073/pnas.1324189111
URL http://www.pnas.org/content/111/7/2758.full.pdf
Languageen angielski
Score (nominal)45
ScoreMinisterial score = 45.0, 20-12-2017, ArticleFromJournal
Ministerial score (2013-2016) = 45.0, 20-12-2017, ArticleFromJournal
Publication indicators WoS Impact Factor: 2014 = 9.674 (2) - 2014=10.563 (5)
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